APPLICATION
Application Note
The peptide is used for blocking the activity of anti-caspase-9 (GTX22013).Incubating the peptide with equal volume of antibody for 30 min at 37ºC usually completely blocksthe antibody activity in Western blotting.
PROPERTIES
Form
Liquid
Buffer
PBS, 0.1% BSA
Preservative
0.02% Sodium azide
Storage
Store the peptide at -20ºC, stable for one year.
Concentration
0.20 mg/ml (Please refer to the vial label for the specific concentration.)
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Caspase 9 , Apaf-3 , Apaf3 , Ice-Lap6 , Mch6 , Ppp1R56 , Casp9
Background
Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase-9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
Research Area
REFERENCE
There are currently no references for Caspase 9 peptide (GTX27885). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Caspase 9 peptide (GTX27885). Be the first to share your experience with this product.