GeneTex

  • Country / Location Selection

United States (US)

Cathepsin D Heavy chain antibody

Anti-Cathepsin D Heavy chain antibody used in Western Blot (WB). GTX56270

Cat. No. GTX56270

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Cathepsin D Heavy chain products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of Cathepsin D Heavy chain. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cathepsin D , CLN10 , CPSD , HEL-S-130P

Cellular Localization

Lysosome

Background

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-Cathepsin D Heavy chain antibody used in Western Blot (WB). GTX56270

GTX56270 WB Image

WB analysis of UV-treated HeLa (A), mouse kidney (B), rat kidney (C) whole cell lysates using GTX56270 Cathepsin D Heavy chain antibody.

REFERENCE

There are currently no references for Cathepsin D Heavy chain antibody (GTX56270). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for Cathepsin D Heavy chain antibody (GTX56270). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399