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Cathepsin D antibody [GT1232]

Recombinant antibody
Anti-Cathepsin D antibody [GT1232] used in Western Blot (WB). GTX01540
Anti-Cathepsin D antibody [GT1232] used in IHC (Paraffin sections) (IHC-P). GTX01540
Anti-Cathepsin D antibody [GT1232] used in Western Blot (WB). GTX01540
Anti-Cathepsin D antibody [GT1232] used in IHC (Paraffin sections) (IHC-P). GTX01540

Cat. No. GTX01540

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 GT1232

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Cathepsin D products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

45 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human Cathepsin D.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CLN10,CPSD,CTSD,HELS130P,cathepsin D,Cathepsin D

Cellular Localization

Lysosome,Melanosome,Secreted,Extracellular space

Background

This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-Cathepsin D antibody [GT1232] used in Western Blot (WB). GTX01540

GTX01540 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with Cathepsin D antibody [GT1232] (GTX01540) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
The observed M.W. is based on the publication: PMID: 28903038

Anti-Cathepsin D antibody [GT1232] used in IHC (Paraffin sections) (IHC-P). GTX01540

GTX01540 IHC-P Image

IHC-P analysis of mouse heart tissue section using GTX01540 Cathepsin D antibody [GT1232].
Dilution : 1:100

Anti-Cathepsin D antibody [GT1232] used in Western Blot (WB). GTX01540

GTX01540 WB Image

WB analysis of various samples using GTX01540 Cathepsin D antibody [GT1232].
Dilution : 1:1000
Loading : 25 μg

Anti-Cathepsin D antibody [GT1232] used in IHC (Paraffin sections) (IHC-P). GTX01540

GTX01540 IHC-P Image

IHC-P analysis of human brain tissue section using GTX01540 Cathepsin D antibody [GT1232].
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399