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Cathepsin K antibody, Internal

Anti-Cathepsin K antibody, Internal used in Western Blot (WB). GTX81488
Anti-Cathepsin K antibody, Internal used in Flow cytometry (FACS). GTX81488
Anti-Cathepsin K antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX81488

Cat. No. GTX81488

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, FACS

Reactivity

 Human
Package
400 μl ($399)
See all Cathepsin K products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:10-1:50
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

Predict Reactivity

Rabbit, Bovine, Pig, Monkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 207-237 amino acids from the Central region of human CTSK.

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cathepsin K , CTS02 , CTSO , CTSO1 , CTSO2 , PKND , PYCD

Cellular Localization

Lysosome

Background

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013]

Database

Research Area

DATA IMAGES

Anti-Cathepsin K antibody, Internal used in Western Blot (WB). GTX81488

GTX81488 WB Image

WB analysis of 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Cathepsin K (Lane 2) using GTX81488 Cathepsin K antibody, Internal.

Anti-Cathepsin K antibody, Internal used in Flow cytometry (FACS). GTX81488

GTX81488 FACS Image

FACS analysis of ZR-75-1 cells using GTX81488 Cathepsin K antibody, Internal.
Top histogram : negative control
Bottom histogram : ZR-75-1 cells

Anti-Cathepsin K antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX81488

GTX81488 IHC-P Image

IHC-P analysis of human breast carcinoma using GTX81488 Cathepsin K antibody, Internal.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399