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Cathepsin V (cleaved Leu114) antibody

Anti-Cathepsin V (cleaved Leu114) antibody used in Western Blot (WB). GTX86922

Cat. No. GTX86922

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all Cathepsin V products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

Product Note

Cathepsin V (cleaved Leu114) antibody detects endogenous levels of fragment of activated Cathepsin V resulting from cleavage adjacent to Leu114.

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Cathepsin V (95-144).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CATL2 , CTSL2 , CTSU , CTSV , cathepsin V , Cathepsin V

Cellular Localization

Lysosome

Background

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]

Database

Research Area

DATA IMAGES

Anti-Cathepsin V (cleaved Leu114) antibody used in Western Blot (WB). GTX86922

GTX86922 WB Image

WB analysis of HeLa cells treated with etoposide using GTX86922 Cathepsin V (cleaved Leu114) antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399