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Cav1.3 antibody

Anti-Cav1.3 antibody used in Western Blot (WB). GTX54755
Anti-Cav1.3 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54755

Cat. No. GTX54755

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-Fr, IP

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all Cav1.3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-Fr Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

250 kDa. ( Note )

Predict Reactivity

Hamster(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.85 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Peptide (C)DNKVTIDDYQEEAEDKD, corresponding to amino acid residues 859-875 (Intracellular loop between domains II and III) of rat CaV1.3 (Accession  : P27732).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

calcium voltage-gated channel subunit alpha1 D

Cellular Localization

Membrane; Multi-pass membrane protein

Background

has high voltage L-type calcium channel activity that is sensitive to dihydropyridines [RGD, Feb 2006]

Database

Research Area

DATA IMAGES

Anti-Cav1.3 antibody used in Western Blot (WB). GTX54755

GTX54755 WB Image

WB analysis of rat brain membrane lysate using GTX54755 Cav1.3 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

Anti-Cav1.3 antibody used in IHC (Frozen sections) (IHC-Fr). GTX54755

GTX54755 IHC-Fr Image

IHC-Fr analysis of rat DRG tissue using GTX54755 Cav1.3 antibody. Staining appears in clusters of cells (green) but not in axons. Staining of neurofilament 200 demonstrates partial overlap with CaV1.3 in neuronal staining but not in axons (red).

REFERENCE

Application Reference

Osuru HP et al. Front Cardiovasc Med 2022; 9 : 711421 Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1α Inhibition.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639