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Cav3.2 antibody [S55-10]

Anti-Cav3.2 antibody [S55-10] used in IHC (Frozen sections) (IHC-Fr). GTX41984

Cat No. GTX41984

Host

Mouse

Clonality

Monoclonal

Clone Name

S55-10

Isotype

IgG1

Application

WB, ICC/IF, IHC-Fr, IP

Reactivity

Human, Mouse, Rat
Package
100 μg ($339)

APPLICATION

Application Note

We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).

Calculated MW

259 kDa. ( Note )

Product Note

No cross-reactivity against Cav1.3

PROPERTIES

Form

Liquid

Buffer

PBS pH7.4, 50% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fusion protein amino acids 1019-1293 (II-III loop) of human Cav3.2, accession number O95180

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

calcium voltage-gated channel subunit alpha1 H , CACNA1HB , Cav3.2 , ECA6 , EIG6 , HALD4

Cellular Localization

Cell membrane

Background

This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Cav3.2 antibody [S55-10] used in IHC (Frozen sections) (IHC-Fr). GTX41984

GTX41984 IHC-Fr Image

IHC analysis of Cav3.2 in frozen sections of mouse brain extract using GTX41984.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Package List Price ($)
$ 339