APPLICATION
Application Note
We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).
Calculated MW
Product Note
No cross-reactivity against Cav1.3
PROPERTIES
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Fusion protein amino acids 1019-1293 (II-III loop) of human Cav3.2, accession number O95180
Purification
Protein G Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
calcium voltage-gated channel subunit alpha1 H , CACNA1HB , Cav3.2 , ECA6 , EIG6 , HALD4
Cellular Localization
Cell membrane
Background
This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX41984 IHC-Fr Image
IHC analysis of Cav3.2 in frozen sections of mouse brain extract using GTX41984.
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REFERENCE
There are currently no references for Cav3.2 antibody [S55-10] (GTX41984). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Cav3.2 antibody [S55-10] (GTX41984). Be the first to share your experience with this product.