APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1 - 2 μg/mL |
5 μg/mL |
Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
HEK293 Cell Lysate(GTX27902)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Cav3.2 antibody was raised against a 16 amino acid peptide near the center of human Cav3.2.The immunogen is located within amino acids 1010 - 1060 of Cav3.2.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
calcium voltage-gated channel subunit alpha1 H , CACNA1HB , Cav3.2 , ECA6 , EIG6 , HALD4
Cellular Localization
Cell membrane
Background
This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX31939 WB Image
WB analysis of 293 cell lysate in (A) the absence and (B) the presence of blocking peptide using GTX31939 Cav3.2 antibody. Working concentration : 1 μg/ml
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GTX31939 IHC-P Image
IHC-P analysis of mouse brain tissue using GTX31939 Cav3.2 antibody. Working concentration : 20 μg/ml
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GTX31939 IHC-P Image
IHC-P analysis of mouse brain tissue using GTX31939 Cav3.2 antibody. Working concentration : 5 μg/ml
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REFERENCE
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REVIEW
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