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Caveolin 1 (phospho Tyr14) antibody

Anti-Caveolin 1 (phospho Tyr14) antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50156
Anti-Caveolin 1 (phospho Tyr14) antibody used in Western Blot (WB). GTX50156

Cat. No. GTX50156

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Caveolin 1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
ICC/IF 1:100-1:200
Not tested in other applications.

Calculated MW

20 kDa. ( Note )

Predict Reactivity

Rat(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide sequence around phosphorylation site of tyrosine 14 (H-L-Y(p)-T-V) derived from human Caveolin 1.

Purification

Purified by antigen-affinity chromatography. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

caveolin 1 , BSCL3 , CGL3 , LCCNS , MSTP085 , PPH3 , VIP21

Background

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]

Database

Research Area

DATA IMAGES

Anti-Caveolin 1 (phospho Tyr14) antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX50156

GTX50156 ICC/IF Image

ICC/IF analysis of methanol-fixed HeLa cells using GTX50156 Caveolin 1 (phospho Tyr14) antibody.

Anti-Caveolin 1 (phospho Tyr14) antibody used in Western Blot (WB). GTX50156

GTX50156 WB Image

WB analysis of extracts from 3T3 cells untreated (lane 1) or treated with H2O2 (lane 2) using GTX50156 Caveolin 1 (phospho Tyr14) antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399