GeneTex
United States (US)

ChREBP antibody

GTX30677_338_IHC-P_18121410_887.jpg
GTX30677_237_ICC-IF_18121410_866.jpg
GTX30677_1477_WB_18121410_530.jpg
GTX30677_236_ICC-IF_18121410_492.jpg
GTX30677_339_IHC-P_18121410_656.jpg

Cat No. GTX30677

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P, IP, ChIP assay
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
ICC/IF 1:100 - 1:500
IHC-P 1:100
IP 1:10 - 1:500
ChIP assay 1:10 - 1:500
Not tested in other applications.

Calculated MW

93 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS, 0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A C-terminal synthetic peptide made to the human CHREBP protein sequence (between residues 800-852). [UniProt# Q9NP71, Isoform 1/Alpha]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Mlx Interacting Protein Like,Chrebp,Mio,Mlx,Mondob,Wbscr14,Ws-Bhlh,Bhlhd14,Mlxipl

Cellular Localization

Nucleus

Background

This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX30677_338_IHC-P_18121410_887.jpg

GTX30677 IHC-P Image

IHC-P analysis of human colon tissue using GTX30677 ChREBP antibody.

GTX30677_237_ICC-IF_18121410_866.jpg

GTX30677 ICC/IF Image

ICC/IF analysis of human hepatocyte using GTX30677 ChREBP antibody.
Red : primary antibody
Blue : DAPI

GTX30677_1477_WB_18121410_530.jpg

GTX30677 WB Image

WB analysis of human hepatocyte lysate using GTX30677 ChREBP antibody.
Loading : 20μg

GTX30677_236_ICC-IF_18121410_492.jpg

GTX30677 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX30677 ChREBP antibody.
Green : primary antibody
Red : Tubulin
Blue : DAPI
Dilution : 1:200
Fixation : 10% formalin
Permibilization : 0.5% Triton-X100

GTX30677_339_IHC-P_18121410_656.jpg

GTX30677 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX30677 ChREBP antibody.

REFERENCE
Package List Price ($)
$ 339