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ChREBP antibody

Anti-ChREBP antibody used in IHC (Paraffin sections) (IHC-P). GTX30677
Anti-ChREBP antibody used in Western Blot (WB). GTX30677
Anti-ChREBP antibody used in IHC (Paraffin sections) (IHC-P). GTX30677
Anti-ChREBP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30677
Anti-ChREBP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30677

Cat. No. GTX30677

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IP, ChIP assay

Reactivity

 Human, Mouse, Rat
Package
100 μl ($449)
See all ChREBP products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF 1:100 - 1:500
IHC-P 1:100
IP 1:10 - 1:500
ChIP assay 1:10 - 1:500
Not tested in other applications.

Calculated MW

93 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A C-terminal synthetic peptide made to the human CHREBP protein sequence (between residues 800-852). [UniProt# Q9NP71, Isoform 1/Alpha]

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

RRID

AB_626087

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

MLX interacting protein like , CHREBP , MIO , MLX , MONDOB , WBSCR14 , WS-bHLH , bHLHd14

Cellular Localization

Nucleus

Background

This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-ChREBP antibody used in IHC (Paraffin sections) (IHC-P). GTX30677

GTX30677 IHC-P Image

IHC-P analysis of human colon tissue using GTX30677 ChREBP antibody.

Anti-ChREBP antibody used in Western Blot (WB). GTX30677

GTX30677 WB Image

WB analysis of human hepatocyte lysate using GTX30677 ChREBP antibody.
Loading : 20μg

Anti-ChREBP antibody used in IHC (Paraffin sections) (IHC-P). GTX30677

GTX30677 IHC-P Image

IHC-P analysis of mouse liver tissue using GTX30677 ChREBP antibody.

Anti-ChREBP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30677

GTX30677 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX30677 ChREBP antibody.
Green : primary antibody
Red : Tubulin
Blue : DAPI
Dilution : 1:200
Fixation : 10% formalin
Permibilization : 0.5% Triton-X100

Anti-ChREBP antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX30677

GTX30677 ICC/IF Image

ICC/IF analysis of human hepatocyte using GTX30677 ChREBP antibody.
Red : primary antibody
Blue : DAPI

REFERENCE

Application Reference

Wang H et al. J Cell Mol Med 2020; 24 (2) : 1399-1412 Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes.
Dreja T et al. Diabetologia 2010; 53 (2) : 309-20 Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model of the metabolic syndrome.
Application : IHC-P
Reactivity : Mouse
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 449