APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.25-0.5μg/ml for 30 minutes at RT |
Assay dependent |
Note :
IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95ºC followed by cooling at RT for 20 minutes.
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Not tested in other applications.
Calculated MW
Product Note
We do not recommend use of this product for Rat samples.
PROPERTIES
Form
Liquid
Buffer
PBS, 0.05% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant full-length human chromogranin A protein
Purification
Protein A/G purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
CGA , CHGA , chromogranin A , Chromogranin A
Cellular Localization
Cytoplasmic vesicle,Secretory vesicle lumen,Secretory vesicle membrane,Secreted,Secretory vesicle
Background
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]
Database
Research Area
DATA IMAGES
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GTX34600 Protein Array Image
Analysis of Protein Array containing more than 19,000 full-length human proteins using Chromogranin A (CHGA) Mouse Monoclonal Antibody (CHGA/413). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.
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GTX34600 IHC-P Image
IHC-P analysis of human adrenal gland tissue using GTX34600 Chromogranin A antibody [CGA/413].
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GTX34600 IHC-P Image
IHC-P analysis of human parathyroid tissue using GTX34600 Chromogranin A antibody [CGA/413].
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GTX34600 IHC-P Image
IHC-P analysis of human pancreas tissue using GTX34600 Chromogranin A antibody [CGA/413].
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GTX34600 IHC-P Image
IHC-P analysis of human pheochromocytoma tissue using GTX34600 Chromogranin A antibody [CGA/413].
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REFERENCE
There are currently no references for Chromogranin A antibody [CGA/413] (GTX34600). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Chromogranin A antibody [CGA/413] (GTX34600). Be the first to share your experience with this product.