GeneTex
United States (US)

Chromogranin A antibody

Chromogranin-A-antibody-GTX17064-IHC-1_18121409_929.jpg

Cat No. GTX17064

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P, IHC
Reactivity Human
APPLICATION

Application Note

IHC-P: 1/25 - 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol with 10 mM citrate buffer, pH 6.0. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

51 kDa. ( Note )

Positive Control

Pancreas
PROPERTIES

Form

Liquid

Buffer

Preservative: Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

C-terminal half of Chromogranin A, purified from urine of patients with carcinoid syndrome.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Chromogranin A,Cga,Chga

Cellular Localization

Neuroendocrine and endocrine secretory granules.

Background

Chromogranin A (a protein of 439 amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, phenochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

Database

Research Area

DATA IMAGES
Chromogranin-A-antibody-GTX17064-IHC-1_18121409_929.jpg

GTX17064 IHC Image

IHC Image using GTX17064 - Detection of Chromogranin A by IHC in Human Pancreas

Package List Price ($)
$ 359