GeneTex
  • Country / Location Selection

United States (US)

Claudin 16 antibody, C-term

Anti-Claudin 16 antibody, C-term used in Western Blot (WB). GTX47762

Cat No. GTX47762

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human
Package
50 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-2.5 ug/ml
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

Positive Control

human fetal kidney

PROPERTIES

Form

Liquid

Buffer

1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a C-terminal region of Human Claudin 16

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

claudin 16 , HOMG3 , PCLN1

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28. [provided by RefSeq, Jun 2010]

Database

Research Area

DATA IMAGES

Anti-Claudin 16 antibody, C-term used in Western Blot (WB). GTX47762

GTX47762 WB Image

WB analysis of human fetal kidney tissue using GTX47762 Claudin 16 antibody at 0.2-1μg/ml.

REFERENCE

There are currently no references for Claudin 16 antibody, C-term (GTX47762). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Claudin 16 antibody, C-term (GTX47762). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf