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Claudin 2 antibody, N-term

Orthogonal
Anti-Claudin 2 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX81901
Anti-Claudin 2 antibody, N-term used in Western Blot (WB). GTX81901
Anti-Claudin 2 antibody, N-term used in Western Blot (WB). GTX81901

Cat. No. GTX81901

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
400 μl ($399)
See all Claudin 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:10-1:50
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

Predict Reactivity

Bovine(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 135-164 amino acids from the N-terminal region of human Claudin 2 (CLDN2).

Purification

Protein A purified, followed by peptide affinity purification.

Conjugation

Unconjugated

RRID

AB_11179521

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

claudin 2

Cellular Localization

Cell membrane

Background

This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.[provided by RefSeq, Jan 2010]

Database

Research Area

DATA IMAGES

Anti-Claudin 2 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX81901

GTX81901 IHC-P Image

IHC-P analysis of human hepatocarcinoma using GTX81901 Claudin 2 antibody, N-term.

Anti-Claudin 2 antibody, N-term used in Western Blot (WB). GTX81901

GTX81901 WB Image

WB analysis of mouse heart tissue lysate (35ug/lane) using GTX81901 Claudin 2 antibody, N-term.

Anti-Claudin 2 antibody, N-term used in Western Blot (WB). GTX81901

GTX81901 WB Image

Orthogonal

The data was published in the journal Oncotarget in 2015.PMID: 26087186

REFERENCE

Application Reference

Luo Y et al. Oncotarget 2015; 6 (26) : 22564-74 Regulation of migration and invasion by Toll-like receptor-9 signaling network in prostate cancer.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399