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Claudin 4 antibody

Anti-Claudin 4 antibody used in IHC (Paraffin sections) (IHC-P). GTX00667
Anti-Claudin 4 antibody used in Western Blot (WB). GTX00667

Cat. No. GTX00667

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399)
See all Claudin 4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

Predict Reactivity

Rabbit, Sheep, Bovine, Dog, Pig, Horse, Xenopus(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human Claudin 4, corresponding to a region within C-terminal amino acids.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CLDN4 , CPER , CPETR , CPETR1 , WBSCR8 , claudin 4 , hCPER , Claudin 4

Cellular Localization

Cell junction,Tight junction,Cell membrane

Background

The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]

Database

Research Area

DATA IMAGES

Anti-Claudin 4 antibody used in IHC (Paraffin sections) (IHC-P). GTX00667

GTX00667 IHC-P Image

IHC-P analysis of human urothelial cancer tissue using GTX00667 Claudin 4 antibody.
Dilution : 1:100
Antigen retrieval : Heat mediated antigen retrieval step in citrate buffer

Anti-Claudin 4 antibody used in Western Blot (WB). GTX00667

GTX00667 WB Image

WB analysis of HeLa cell lysate using GTX00667 Claudin 4 antibody. The lane on the left was treated with the antigen-specific peptide.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399