GeneTex
United States (US)

Claudin 4 antibody

GTX31496_1107_IHC-P_20180221_18121410_712.jpg
GTX31496_2687_WB_20180221_18121410_903.jpg

Cat No. GTX31496

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
IHC-P 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

Positive Control

HeLa Cell Lysate

Specificity/Sensitivity

At least four isoforms of CLAUDIN4 are known to exist; CLAUDIN4 antibody will detect all four isoforms
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CLAUDIN4 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human CLAUDIN4.The immunogen is located within the last 50 amino acids of CLAUDIN4.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Claudin 4,Cpe-R,Cper,Cpetr,Cpetr1,Wbscr8,Hcpe-R,Cldn4

Background

The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]

Database

Research Area

DATA IMAGES
GTX31496_1107_IHC-P_20180221_18121410_712.jpg

GTX31496 IHC-P Image

IHC-P analysis of human colon tissue using GTX31496 Claudin 4 antibody.
Working concentration : 20 μg/ml

GTX31496_2687_WB_20180221_18121410_903.jpg

GTX31496 WB Image

WB analysis of HeLa cell lysate using GTX31496 Claudin 4 antibody.
Working concentration : 0.5 μg/ml