GeneTex
  • Country / Location Selection

United States (US)

Claudin 7 antibody

Anti-Claudin 7 antibody used in Western Blot (WB). GTX66616
Anti-Claudin 7 antibody used in IHC (Paraffin sections) (IHC-P). GTX66616
Anti-Claudin 7 antibody used in Immunoprecipitation (IP). GTX66616

Cat No. GTX66616

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, IP

Reactivity

Human, Mouse, Rat
Package
100 μl ($349)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
IP 1:50-1:200
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.2, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 171-220 of Human Claudin-7.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

claudin 7 , CEPTRL2 , CLDN-7 , CPETRL2 , Hs.84359 , claudin-1

Cellular Localization

Cell membrane

Background

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-Claudin 7 antibody used in Western Blot (WB). GTX66616

GTX66616 WB Image

WB analysis of various samples using GTX66616 Claudin 7 antibody.
Lane1 : HCC827 whole cell lysate(40ug)
Lane2 : The Lung tissue lysate of Mouse(40ug)
Lane3 : The Lung tissue lysate of Rat(40ug)
Lane4 : A549 whole cell lysate(40ug)
Lane5 : L02 whole cell lysate(40ug)
Dilution : 1:500

Anti-Claudin 7 antibody used in IHC (Paraffin sections) (IHC-P). GTX66616

GTX66616 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX66616 Claudin 7 antibody.
Dilution : 1:100

Anti-Claudin 7 antibody used in Immunoprecipitation (IP). GTX66616

GTX66616 IP Image

IP analysis of Hela cell lysate using GTX66616 Claudin 7 antibody (Lane 2 and 3) and nonspecific IgG control antibody (Lane 4 and 5) compared to the input control (Lane 1).
Upward arrow : supernatant
Downward arrow : Immunoprecipitants

REFERENCE

There are currently no references for Claudin 7 antibody (GTX66616). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Claudin 7 antibody (GTX66616). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 349