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Coagulation factor III/Tissue Factor antibody

Anti-Coagulation factor III/Tissue Factor antibody used in Western Blot (WB). GTX02325
Anti-Coagulation factor III/Tissue Factor antibody used in Immunoprecipitation (IP). GTX02325

Cat No. GTX02325

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IP

Reactivity

Human
Package
100 μl ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:2000
IP 1-4 μl/mg of lysate
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Observed MW

50 kDa. The observed M.W. is based on the following publication. PMID: 30622378

PROPERTIES

Form

Liquid

Buffer

0.2μm-filtered PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human Coagulation Factor III / Tissue Factor / CD142 protein

Purification

Purified by Protein A and Antigen Affinity

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

coagulation factor III, tissue factor , CD142 , TF , TFA

Background

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-Coagulation factor III/Tissue Factor antibody used in Western Blot (WB). GTX02325

GTX02325 WB Image

WB analysis of A431 whole cell lysate (Lane A) using GTX02325 Coagulation factor III/Tissue Factor antibody.
Dilution : 1:500
Loading : 30 μg

Anti-Coagulation factor III/Tissue Factor antibody used in Immunoprecipitation (IP). GTX02325

GTX02325 IP Image

IP analysis of A431 whole cell lysate using GTX02325 Coagulation factor III/Tissue Factor antibody.
IP antibody : 2 μl per 0.5 mg total whole cell lysate
Dilution : 1:100
50 % Protein G agarose : 15 μl

REFERENCE

There are currently no references for Coagulation factor III/Tissue Factor antibody (GTX02325). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Coagulation factor III/Tissue Factor antibody (GTX02325). Be the first to share your experience with this product.
Package List Price ($)
$ 339