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Coagulation factor III/Tissue Factor antibody

Anti-Coagulation factor III/Tissue Factor antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04323
Anti-Coagulation factor III/Tissue Factor antibody used in Western Blot (WB). GTX04323
Anti-Coagulation factor III/Tissue Factor antibody used in Western Blot (WB). GTX04323

Cat. No. GTX04323

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF

Reactivity

 Human
Package
100 μl ($399)
See all Coagulation factor III/Tissue Factor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
ICC/IF 1:100-1:500
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Predict Reactivity

Sheep, Bovine, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human F3(Accession P13726), corresponding to amino acid residues I269-S295.

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

coagulation factor III, tissue factor , CD142 , TF , TFA

Cellular Localization

Secreted

Background

This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-Coagulation factor III/Tissue Factor antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04323

GTX04323 ICC/IF Image

ICC/IF analysis of PFA fixed HeLa cells using GTX04323 Coagulation factor III/Tissue Factor antibody.
Red : Primary antibody
Green : beta tubulin
Permeabilization : 0.1% Triton X-100
Dilution : 1:200

Anti-Coagulation factor III/Tissue Factor antibody used in Western Blot (WB). GTX04323

GTX04323 WB Image

WB analysis of MDA-MB-231 whole cell lysate using GTX04323 Coagulation factor III/Tissue Factor antibody. The lane on the left was treated with blocking peptide.

Anti-Coagulation factor III/Tissue Factor antibody used in Western Blot (WB). GTX04323

GTX04323 WB Image

WB analysis of MDA-MB-231 whole cell lysate using GTX04323 Coagulation factor III/Tissue Factor antibody. The lane on the left was treated with blocking peptide.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399