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Cofilin 2 antibody, C-term

Anti-Cofilin 2 antibody, C-term used in Western Blot (WB). GTX89482
Anti-Cofilin 2 antibody, C-term used in Western Blot (WB). GTX89482
Anti-Cofilin 2 antibody, C-term used in Western Blot (WB). GTX89482
Anti-Cofilin 2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89482

Cat. No. GTX89482

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Rat
Package
100 μg ($399)
See all Cofilin 2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.01-0.03μg/ml
IHC-P 3.75μg/ml
Not tested in other applications.

Calculated MW

19 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89482-PEP).

Product Note

This antibody is expected to recognise both reported isoforms (NP_068733 and NP_619579)

Predict Reactivity

Mouse, Dog, Pig(>80% identity)

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-DIKDRSTLGEK, from the C Terminus of the protein sequence according to NP_068733.1; NP_619579.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cofilin 2 , NEM7

Cellular Localization

Cytoplasm, cytoskeleton

Background

This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

Database

Research Area

DATA IMAGES

Anti-Cofilin 2 antibody, C-term used in Western Blot (WB). GTX89482

GTX89482 WB Image

WB analysis of HEK293 overexpressing human muscle Cofilin 2 (mock transfection in first lane) using GTX89482 Cofilin 2 antibody, C-term.

Anti-Cofilin 2 antibody, C-term used in Western Blot (WB). GTX89482

GTX89482 WB Image

WB analysis of rat skeletal muscle lysate using GTX89482 Cofilin 2 antibody, C-term.
Dilution : 0.001μg/ml
Loading : 35μg protein in RIPA buffer

Anti-Cofilin 2 antibody, C-term used in Western Blot (WB). GTX89482

GTX89482 WB Image

WB analysis of human skeletal muscle lysate using GTX89482 Cofilin 2 antibody, C-term.
Dilution : 0.003μg/ml
Loading : 35μg protein in RIPA buffer

Anti-Cofilin 2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89482

GTX89482 IHC-P Image

IHC-P analysis of human heart using GTX89482 Cofilin 2 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.75μg/ml

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399