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Collagen III antibody [1E7-D7/Col3]

Anti-Collagen III antibody [1E7-D7/Col3] used in IHC (Paraffin sections) (IHC-P). GTX60940

Cat. No. GTX60940

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 1E7-D7/Col3

Isotype

 IgG1

Application

 WB, IHC-P, IHC-Fr, ELISA

Reactivity

 Human, Rat, Dog, Kangaroo rat
Package
100 μl ($399)
See all Collagen III products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

139 kDa. ( Note )

Product Note

This antibody is highly specific for type III collagen. It has been shown to have no cross-ractivity with type I and V collagens by ELISA and immunoblotting. There is no evidence for cross-reactivity with other connective tissue proteins (laminin, fibronectin, elastin).

PROPERTIES

Form

Liquid

Buffer

0.01M Phosphate buffer, 0.5M NaCl

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Acid-digested pepsin soluble human type III collagen

Purification

Protein-A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

collagen type III alpha 1 chain , EDS4A , EDSVASC

Background

This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]

Database

Research Area

DATA IMAGES

Anti-Collagen III antibody [1E7-D7/Col3] used in IHC (Paraffin sections) (IHC-P). GTX60940

GTX60940 IHC-P Image

Paraffin-embedded human bronchus tissue immunostained with GTX60940

REFERENCE

Application Reference

TH de Castro et al. Int J Morphol 2024; 42 (2) : 256-260 Alpaca (Vicugna pacos) Skin Analyzed Under Architecture and Structure
Application : IHC-P
Askaripour M et al. Iran J Basic Med Sci 2022; 25 (11) : 1317-1325 Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a.
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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399