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Collagen III antibody [FH-7A]

Anti-Collagen III antibody [FH-7A] used in IHC (Frozen sections) (IHC-Fr). GTX26310
Anti-Collagen III antibody [FH-7A] used in IHC (Paraffin sections) (IHC-P). GTX26310

Cat No. GTX26310

Host Mouse
Clonality Monoclonal
Clone Name FH-7A
Isotype IgG1
Application WB, IHC-P, IHC-Fr, Dot, ELISA
Reactivity Human, Rat, Rabbit
Package
100 μl ($369)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
IHC-P Assay dependent
IHC-Fr 1:4,000
Dot Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

139 kDa. ( Note )

Positive Control

human skin

Specificity/Sensitivity

Type III collagen, [a1(III)]3 ,is an approx. 300 kDa molecule, found predominantly in skin, blood vessels, liver, placenta, tongue, and thymus. Collagen type III forms cofibrils with type I and/or V collagens in a number of tissues of mesenchymal origin, such as skin, tendon, ligaments, and bone. This collagen type is involved, directly or indirectly in several genetic diseases, including Ehlers-Danlos type IV disease.
PROPERTIES

Form

Liquid

Buffer

Ascites, 15 mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

human collagen type III

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Collagen Type Iii Alpha 1 Chain,Eds4A,Edsvasc,Col3A1

Background

Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in the gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.

Database

Research Area

DATA IMAGES
Anti-Collagen III antibody [FH-7A] used in IHC (Frozen sections) (IHC-Fr). GTX26310

GTX26310 IHC-Fr Image

IHC-Fr analysis of rat skin tissue using GTX26310 Collagen III antibody [FH-7A] at 1:8,000.

Anti-Collagen III antibody [FH-7A] used in IHC (Paraffin sections) (IHC-P). GTX26310

GTX26310 IHC-P Image

IHC-P analysis of rat skin using GTX26310 Collagen III antibody [FH-7A] at 1:4000.

REFERENCE
REVIEW
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Package List Price ($)
$ 369