GeneTex

  • Country / Location Selection

United States (US)

Complement Factor D antibody

Anti-Complement Factor D antibody used in IHC (Paraffin sections) (IHC-P). GTX33107
Anti-Complement Factor D antibody used in Western Blot (WB). GTX33107
Anti-Complement Factor D antibody used in IHC (Paraffin sections) (IHC-P). GTX33107

Cat. No. GTX33107

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Complement Factor D products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 26-253 of human CFD (NP_001919.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887695

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

complement factor D , ADIPSIN , ADN , DF , PFD

Cellular Localization

Secreted

Background

This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-Complement Factor D antibody used in IHC (Paraffin sections) (IHC-P). GTX33107

GTX33107 IHC-P Image

IHC-P analysis of human stomach tissue using GTX33107 Complement Factor D antibody.
Dilution : 1:100

Anti-Complement Factor D antibody used in Western Blot (WB). GTX33107

GTX33107 WB Image

WB analysis of various sample lysates using GTX33107 Complement Factor D antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Anti-Complement Factor D antibody used in IHC (Paraffin sections) (IHC-P). GTX33107

GTX33107 IHC-P Image

IHC-P analysis of human prostate tissue using GTX33107 Complement Factor D antibody.
Dilution : 1:100

REFERENCE

Application Reference

Banda NK et al. J Immunol 2017; (Epub) Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.
Application : IHC-P
Reactivity : Mouse
Submit a Reference

REVIEW

There are currently no reviews for Complement Factor D antibody (GTX33107). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399