GeneTex
United States (US)

Connexin 43 antibody, Internal

GTX88424_2326_WB_18121411_949.jpg

Cat No. GTX88424

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.1-1μg/ml
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88424-PEP).

Predict Reactivity

Dog, Pig(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-QPFDFPDDNQNSKK, from the internal region of the protein sequence according to NP_000156.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Gap Junction Protein Alpha 1,Avsd3,Cmdr,Cx43,Ekvp,Ekvp3,Gjal,Hlhs1,Hss,Oddd,Ppkca,Gja1

Background

This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]

Database

Research Area

DATA IMAGES
GTX88424_2326_WB_18121411_949.jpg

GTX88424 WB Image

WB analysis of human (A) and rat (B) heart lysate using GTX88424 Connexin 43 antibody, Internal.
Dilution : 0.1µg/ml
Loading : 35µg protein in RIPA buffer

Package List Price ($)
$ 329