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Cortactin antibody [4C6]

Anti-Cortactin antibody [4C6] used in ELISA (ELISA). GTX60419
Anti-Cortactin antibody [4C6] used in Western Blot (WB). GTX60419
Anti-Cortactin antibody [4C6] used in IHC (Paraffin sections) (IHC-P). GTX60419

Cat. No. GTX60419

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 4C6

Isotype

 IgG1

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μl ($409)
See all Cortactin products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

62 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human CTTN expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cortactin , EMS1

Cellular Localization

Cytoplasm, cytoskeleton,Cell projection, dendrite,Cell membrane,Cell junction

Background

This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]

Database

Research Area

DATA IMAGES

Anti-Cortactin antibody [4C6] used in ELISA (ELISA). GTX60419

GTX60419 ELISA Image

ELISA analysis of antigen using GTX60419 Cortactin antibody [4C6].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng

Anti-Cortactin antibody [4C6] used in Western Blot (WB). GTX60419

GTX60419 WB Image

WB analysis of HeLa (1), A431 (2), MCF-7 (3), SR-BR-3 (4), HepG2 (5) and NIH3T3 (6) cell lysate using GTX60419 Cortactin antibody [4C6].

Anti-Cortactin antibody [4C6] used in IHC (Paraffin sections) (IHC-P). GTX60419

GTX60419 IHC-P Image

IHC-P analysis of cervical cancer tissue (left) and tonsil tissue (right) using GTX60419 Cortactin antibody [4C6].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 409