GeneTex
  • Country / Location Selection

United States (US)

Creatine kinase MT antibody [1A6-C7-G10]

Anti-Creatine kinase MT antibody [1A6-C7-G10] used in Western Blot (WB). GTX49207

Cat No. GTX49207

Host

Mouse

Clonality

Monoclonal

Clone Name

1A6-C7-G10

Isotype

IgG1

Application

WB

Reactivity

Human, Mouse
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human Creatine kinase MT protein fragments expressed in E.coli.

Purification

Affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

UMTCK Antibody , CKMT1B Antibody , creatine kinase, mitochondrial 1B Antibody , CKMT Antibody

Cellular Localization

Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.

Background

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

Database

Research Area

DATA IMAGES

Anti-Creatine kinase MT antibody [1A6-C7-G10] used in Western Blot (WB). GTX49207

GTX49207 WB Image

WB analysis of mouse colon, 293 and A431 lysates using Creatine kinase MT antibody at a dilution of 1:1,000.

REFERENCE

There are currently no references for Creatine kinase MT antibody [1A6-C7-G10] (GTX49207). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Creatine kinase MT antibody [1A6-C7-G10] (GTX49207). Be the first to share your experience with this product.
SDS
Glycerol.pdf
Sodium Azide.pdf