GeneTex

  • Country / Location Selection

United States (US)

CrkL antibody

Cat. No. GTX10907

Reference 1

Host

 Goat

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse
Package
50 μg ($399)
See all CrkL products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/200-1/500

Note :

WB
This antibody detects a band of approximately 33kDa in mouse kidney cell lysates. Overnight incubation with primary antibody is recommended.
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

TBS, 0.5% BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide sequence KIFDPQNPDENE derived from C-terminus of CRKL.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_369790

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CRK like proto-oncogene, adaptor protein

Background

This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009]

Database

Research Area

REFERENCE

Application Reference

Hallock PT et al. Genes Dev 2010; 24 (21) : 2451-61 Dok-7 regulates neuromuscular synapse formation by recruiting Crk and Crk-L.
Application : WB
Reactivity : Mouse
Submit a Reference

REVIEW

There are currently no reviews for CrkL antibody (GTX10907). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399