GeneTex
United States (US)

CtIP antibody

Anti-CtIP antibody used in IHC (Paraffin sections) (IHC-P). GTX31413
Anti-CtIP antibody used in Western Blot (WB). GTX31413
Anti-CtIP antibody used in IHC (Paraffin sections) (IHC-P). GTX31413

Cat No. GTX31413

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

102 kDa. ( Note )

Positive Control

Mouse Spleen Tissue Lysate(GTX27937)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

CtIP antibody was raised against a 14 amino acid synthetic peptide near the center of human CtIP.The immunogen is located within amino acids 430 - 480 of CtIP.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Rb Binding Protein 8, Endonuclease,Com1,Ctip,Jwds,Rim,Sae2,Sckl2,Rbbp8

Background

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-CtIP antibody used in IHC (Paraffin sections) (IHC-P). GTX31413

GTX31413 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX31413 CtIP antibody.
Working concentration : 5 μg/ml

Anti-CtIP antibody used in Western Blot (WB). GTX31413

GTX31413 WB Image

WB analysis of mouse spleen tissue lysate using GTX31413 CtIP antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-CtIP antibody used in IHC (Paraffin sections) (IHC-P). GTX31413

GTX31413 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX31413 CtIP antibody.
Working concentration : 20 μg/ml