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Cyclin D1 antibody [DCS-6]

Anti-Cyclin D1 antibody [DCS-6] used in IHC (Paraffin sections) (IHC-P). GTX73878

Cat No. GTX73878

Host

Mouse

Clonality

Monoclonal

Clone Name

DCS-6

Isotype

IgG2a

Application

IHC-P

Reactivity

Human
Package
1 ml ($599)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:25‐1:50

Note :

IHC-P
Recommendations for antigen retrieval : EDTA buffer pH 8.0 at room temperature for 30 mins.

Not tested in other applications.

Calculated MW

34 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS with <0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Prokaryotic recombinant fusion protein corresponding to human cyclin D1.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

BCL1 , CCND1 , D11S287E , PRAD1 , U21B31 , cyclin D1 , Cyclin D1

Cellular Localization

Nucleus,Cytoplasm,Membrane

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Cyclin D1 antibody [DCS-6] used in IHC (Paraffin sections) (IHC-P). GTX73878

GTX73878 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX73878 Cyclin D1 antibody [DCS-6].

REFERENCE

There are currently no references for Cyclin D1 antibody [DCS-6] (GTX73878). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Cyclin D1 antibody [DCS-6] (GTX73878). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 599