GeneTex
United States (US)

Cyclin D1 peptide

Cat No. GTX28013

Application Blocking
Reactivity Human
Species Human
See all Cyclin D1 products
APPLICATION

Application Note

Blocking peptide for Rabbit polyclonal to Cyclin D1 (GTX27958)
PROPERTIES

Form

Liquid

Buffer

PBS with 100ug BSA 0.1% sodium azide

Storage

Keep as concentrated solution, aliquot and store at 4ºC.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Cyclin D1,Bcl1,D11S287E,Prad1,U21B31,Ccnd1

Cellular Localization

Nuclear

Background

During each cell cycle cyclins undergo periodic accumulation and destruction. As key regulators of the cell cycle the cyclins control important transitions by activating Cdks. Early in the G1 phase of the cell cycle cyclin D1 induction is followed by cyclin E induction. This sequential progression is marked early on in G1 by the activation of Cdk4 and in mid to late G1 by the activation of Cdk2 and the hyperphosphorylation of pRB. The final transition into S phase is thought to be dependent on the increased expression and association of cyclin E and Cdk2.

Research Area

Package List Price ($)
$ 179