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Cyclin D2 antibody

Anti-Cyclin D2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60131
Anti-Cyclin D2 antibody used in IHC (Paraffin sections) (IHC-P). GTX60131
Anti-Cyclin D2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60131
Anti-Cyclin D2 antibody used in IHC (Paraffin sections) (IHC-P). GTX60131

Cat. No. GTX60131

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all Cyclin D2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF 1:50-200
IHC-P 1:50-400
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1% BSA, 50% Glycerol

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human Cyclin D2(150-200).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cyclin D2 , KIAK0002 , MPPH3

Cellular Localization

Nucleus,Cytoplasm,Membrane

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3). [provided by RefSeq, Sep 2014]

Database

Research Area

DATA IMAGES

Anti-Cyclin D2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60131

GTX60131 ICC/IF Image

ICC/IF analysis of A431 cells using GTX60131 Cyclin D2 antibody.
Green : Primary antibody
Blue : DAPI
Dilution : 1:200

Anti-Cyclin D2 antibody used in IHC (Paraffin sections) (IHC-P). GTX60131

GTX60131 IHC-P Image

IHC-P analysis of rat ovary tissue using GTX60131 Cyclin D2 antibody.
Dilution : 1:200

Anti-Cyclin D2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX60131

GTX60131 ICC/IF Image

ICC/IF analysis of A549 cells using GTX60131 Cyclin D2 antibody.
Green : Primary antibody
Blue : DAPI
Dilution : 1:50

Anti-Cyclin D2 antibody used in IHC (Paraffin sections) (IHC-P). GTX60131

GTX60131 IHC-P Image

IHC-P analysis of human flat moss tinea tissue using GTX60131 Cyclin D2 antibody.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399