GeneTex
United States (US)

CysLT1 Receptor antibody [N1], N-term

GTX108112_39750_IHC_19011507_245.jpg
GTX108112_WB_19011507_189.jpg

Cat No. GTX108112

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

Positive Control

293T , HeLaS3 , HepG2
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.7mg/ml

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CysLT 1 receptor. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

CYSLT1 antibody, CYSLT1R antibody, CYSLTR antibody, HG55 antibody, HMTMF81 antibody, MGC46139 antibody, CYSLTR1 antibody, cysteinyl leukotriene receptor 1 antibody, cysteinyl leukotriene D4 receptor antibody, LTD4 receptor antibody, G-protein coupled receptor HG55 antibody

Cellular Localization

Cell membrane

Background

The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung. [provided by RefSeq]
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Database

DATA IMAGES
GTX108112_39750_IHC_19011507_245.jpg

GTX108112 IHC-P Image

Immunohistochemical analysis of paraffin-embedded U373 xenograft, using CysLT 1 receptor(GTX108112) antibody at 1:100 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX108112_WB_19011507_189.jpg

GTX108112 WB Image

Sample(30 μg of whole cell lysate)
A:293T
10% SDS PAGE
GTX108112 diluted at 1:500

Reference
SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169