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CysLT1 Receptor antibody

Anti-CysLT1 Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70521
Anti-CysLT1 Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70521

Cat. No. GTX70521

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
25 μg ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 9 - 22 μg/ml
Not tested in other applications.

Calculated MW

39 kDa. ( Note )

Predict Reactivity

Mouse, Rat, Rabbit, Bovine, Pig, Monkey, Elephant, Gibbon, Gorilla, Marmoset, Panda(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 20 amino acid peptide from C-terminus of human CYSLTR1 / CYSLT1.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_375156

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

cysteinyl leukotriene receptor 1 , CYSLT1 , CYSLT1R , CYSLTR , CYSLTR1 , HMTMF81 , CysLT1 Receptor

Cellular Localization

Cell membrane

Background

This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Database

Research Area

DATA IMAGES

Anti-CysLT1 Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70521

GTX70521 IHC-P Image

IHC-P analysis of human lymph node, hodgkins lymphoma tissue using GTX70521 CysLT1 Receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval

Anti-CysLT1 Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX70521

GTX70521 IHC-P Image

IHC-P analysis of human nasal mucosa, allergic rhinitis, eosinophils tissue using GTX70521 CysLT1 Receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399