APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:500-1:3000 |
Not tested in other applications.
Calculated MW
Positive Control
H1299
PROPERTIES
Form
Liquid
Buffer
PBS, 40% Glycerol
Preservative
0.01% Thimerosal
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Cytochrome P450 2A6. The exact sequence is proprietary.
Purification
Purified by antigen-affinity chromatography.
Conjugation
Unconjugated
RRID
AB_1240680
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
cytochrome P450 family 2 subfamily A member 6 , CPA6 , CYP2A , CYP2A3 , CYPIIA6 , P450C2A , P450PB
Cellular Localization
Endoplasmic reticulum membrane , Microsome membrane
Background
This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq]
Database
Research Area
DATA IMAGES
![Anti-Cytochrome P450 2A6 antibody [C1C2], Internal used in Western Blot (WB). GTX103360](/templates/default/js/lightbox/images/loading.gif "Anti-Cytochrome P450 2A6 antibody [C1C2], Internal used in Western Blot (WB). GTX103360")
|
GTX103360 WB Image
Sample (30 ug of whole cell lysate)
A: H1299
7.5% SDS PAGE
GTX103360 diluted at 1:1000
|
REFERENCE
There are currently no references for Cytochrome P450 2A6 antibody [C1C2], Internal (GTX103360). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Cytochrome P450 2A6 antibody [C1C2], Internal (GTX103360). Be the first to share your experience with this product.
![Anti-Cytochrome P450 2A6 antibody [C1C2], Internal used in Western Blot (WB). GTX103360](/upload/website/prouct_img/small/GTX103360/GTX103360_WB_w_23060119_589.webp "Anti-Cytochrome P450 2A6 antibody [C1C2], Internal used in Western Blot (WB). GTX103360")
![Anti-Cytochrome P450 2A6 antibody [C1C2], Internal used in Western Blot (WB). GTX103360](/upload/website/prouct_img/normal/GTX103360/GTX103360_WB_w_23060119_589.webp "Anti-Cytochrome P450 2A6 antibody [C1C2], Internal used in Western Blot (WB). GTX103360")