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Cytokeratin 5/14 antibody [XM26 + LL002]

Anti-Cytokeratin 5/14 antibody [XM26 + LL002] used in IHC (Paraffin sections) (IHC-P). GTX04713

Cat. No. GTX04713

Host

Mouse

Clonality

Monoclonal

Clone Name

XM26 + LL002

Isotype

IgG1, IgG3

Application

IHC-P

Reactivity

Human
Package
500 μl ($469)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:25-1:150

Note :

IHC-P
Recommendations for antigen retrieval : Citrate Buffer pH 6.0 at room temperature for 30 mins.

Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

batch dependent

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

XM26: Recombinant protein corresponding to 103 amino acid portion of C-terminal region of the human cytokeratin 5 molecule._x000D_ LL002: Synthetic peptide of the extreme C-terminal of human keratin-14

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CK5,DDD,DDD1,EBS2,K5,KRT5,KRT5A,keratin 5,Cytokeratin 5,CK14,EBS3,EBS4,K14,KRT14,NFJ,keratin 14,Cytokeratin 14

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]|This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Cytokeratin 5/14 antibody [XM26 + LL002] used in IHC (Paraffin sections) (IHC-P). GTX04713

GTX04713 IHC-P Image

IHC-P analysis of human tonsil tissue using GTX04713 Cytokeratin 5/14 antibody [XM26 + LL002].
Antigen retrieval : Citrate Buffer pH 6.0

REFERENCE

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REVIEW

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Package List Price ($)
$ 469