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Cytokeratin 7 antibody [RN7]

Anti-Cytokeratin 7 antibody [RN7] used in IHC (Paraffin sections) (IHC-P). GTX01903

Cat. No. GTX01903

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 RN7

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($489)
See all Cytokeratin 7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100

Note :

IHC-P
The recommended fixative is 10% neutral-buffered formalin for paraffin-embedded tissue sections. Heat Induced Epitope Retreival (HIER) was performed in Epitope Retreival Solution pH6.
Not tested in other applications.

Calculated MW

51 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to part of the C-terminal region of the cytokeratin 7 intermediate filament molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

keratin 7 , CK7 , K2C7 , K7 , SCL

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Cytokeratin 7 antibody [RN7] used in IHC (Paraffin sections) (IHC-P). GTX01903

GTX01903 IHC-P Image

IHC-P analysis of invasive breast carcinoma tissue using GTX01903 Cytokeratin 7 antibody [RN7]. Note the intense staining of invasive tumor cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 489