GeneTex
United States (US)

D4 GDI antibody

D4-GDI-antibody_IHC-P_GTX15198-1_18121409_750.jpg
D4-GDI-antibody-GTX15198-IHC-1_18121409_402.jpg

Cat No. GTX15198

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

IHC-P: Use at a dilution of 1/100 for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. WB: Use at a concentration of 1 μg/ml for 2hours. Predicted molecular weight: 23 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

23 kDa. ( Note )

Positive Control

Placenta and tonsil
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.4 containing 1% BSA and 0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length protein (Human).

Purification

Immunogen affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Rho Gdp Dissociation Inhibitor Beta,D4,Gdia2,Gdid4,Lygdi,Ly-Gdi,Rap1Gn1,Rhogdi2,Arhgdib

Cellular Localization

Cytoplasmic and Nuclear

Background

D4 GDI belongs to the family of Rho GDIs or GDP dissociation inhibitors for the Rho/Rac family of small G proteins; consisting of RhoGDI 1, D4 GDI/RhoGDI2 and Rho GDI3. It inhibits the release of GDP from the Rho proteins, essential for GTP loading and activation of GTPase activity. D4 GDI is located in the cytoplasm and in involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas mediated apoptosis.

Database

DATA IMAGES
D4-GDI-antibody_IHC-P_GTX15198-1_18121409_750.jpg

GTX15198 IHC-P Image

Human Placenta stained with anti-D4-GDI antibody (GTX15198)

D4-GDI-antibody-GTX15198-IHC-1_18121409_402.jpg

GTX15198 IHC-P Image

GTX15198 staining D4 GDI in human tonsil by Immunohistochemistry (FFPE-sections).

Package List Price ($)
$ 289