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DAG1 / beta Dystroglycan antibody [43DAG1/8D5]

Anti-DAG1 / beta Dystroglycan antibody [43DAG1/8D5] used in IHC (Frozen sections) (IHC-Fr). GTX01940

Cat. No. GTX01940

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 43DAG1/8D5

Isotype

 IgG2a

Application

 IHC-Fr

Reactivity

 Human, Mouse, Rat, Rabbit, Dog, Hamster, Chicken, Frog
Package
500 μl ($609)
See all DAG1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-Fr 1:50–1:200

Note :

IHC-Fr
Freeze specimen tissue blocks in isopentane chilled in liquid nitrogen.
Not tested in other applications.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic peptide containing 15 of the last 16 amino acids at the extreme C-terminus of the human beta-dystroglycan sequence (PKNMTPYRSPPPYVP-PCOOH).

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dystroglycan 1 , 156DAG , A3a , AGRNR , DAG , LGMDR16 , MDDGA9 , MDDGC7 , MDDGC9

Cellular Localization

Cytoplasm, cytoskeleton , nucleoplasm

Background

This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-DAG1 / beta Dystroglycan antibody [43DAG1/8D5] used in IHC (Frozen sections) (IHC-Fr). GTX01940

GTX01940 IHC-Fr Image

IHC-Fr analysis of human skeletal muscle using GTX01940 DAG1 / beta Dystroglycan antibody [43DAG1/8D5]. Staining is localized in the sarcolemma of the fibers.

REFERENCE

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REVIEW

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Package List Price ($)
$ 609