GeneTex
United States (US)

DCAMKL2 antibody

GTX31404_1013_IHC-P_20180221_18121410_418.jpg
GTX31404_2602_WB_20180221_18121410_289.jpg

Cat No. GTX31404

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

84 kDa. ( Note )

Positive Control

Mouse Cerebrum Tissue Lysate(GTX24022)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

DCAMKL2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human DCAMKL2.The immunogen is located within the last 50 amino acids of DCAMKL2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Doublecortin Like Kinase 2,Cl2,Click-Ii,Click2,Clik2,Dcamkl2,Dcdc3,Dcdc3B,Dck2,Dclk2

Background

This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Sep 2010]

Database

DATA IMAGES
GTX31404_1013_IHC-P_20180221_18121410_418.jpg

GTX31404 IHC-P Image

IHC-P analysis of rat brain tissue using GTX31404 DCAMKL2 antibody.
Working concentration : 5 μg/ml

GTX31404_2602_WB_20180221_18121410_289.jpg

GTX31404 WB Image

WB analysis of rat brain tissue lysate using GTX31404 DCAMKL2 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Package List Price ($)
$ 329