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United States (US)

DCC antibody

Cat No. GTX47825

Host Rabbit
Clonality Polyclonal
Isotype IgG
Reactivity Human, Mouse, Rat
Package
100 μg ($329)
APPLICATION

Calculated MW

158 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Phosphate/Glycine, pH7.2-7.4

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthetic peptide

Purification

Affinity purified using antigen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Dcc Netrin 1 Receptor,Crc18,Crcr1,Hgpps2,Igdcc1,Mrmv1,Ntn1R1,Dcc

Background

Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.

Database

Research Area

REFERENCE
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Package List Price ($)
$ 329