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DCTN2 antibody

Anti-DCTN2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55598
Anti-DCTN2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55598
Anti-DCTN2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55598
Anti-DCTN2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55598
Anti-DCTN2 antibody used in Western Blot (WB). GTX55598

Cat. No. GTX55598

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all DCTN2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:20 - 1:50
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human DCTN2 (NP_006391.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dynactin subunit 2 , DCTN50 , DYNAMITIN , HEL-S-77 , RBP50

Cellular Localization

Membrane

Background

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012]

Database

Research Area

DATA IMAGES

Anti-DCTN2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX55598

GTX55598 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX55598 DCTN2 antibody.
Blue : DAPI

Anti-DCTN2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55598

GTX55598 IHC-P Image

IHC-P analysis of human breast cancer tissue using GTX55598 DCTN2 antibody.
Dilution : 1:100

Anti-DCTN2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55598

GTX55598 IHC-P Image

IHC-P analysis of rat brain tissue using GTX55598 DCTN2 antibody.
Dilution : 1:100

Anti-DCTN2 antibody used in IHC (Paraffin sections) (IHC-P). GTX55598

GTX55598 IHC-P Image

IHC-P analysis of human kidney tissue using GTX55598 DCTN2 antibody.
Dilution : 1:200

Anti-DCTN2 antibody used in Western Blot (WB). GTX55598

GTX55598 WB Image

WB analysis of MCF7 cell lysate using GTX55598 DCTN2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399