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DDB2 antibody [GT1277]

Recombinant antibody
Anti-DDB2 antibody [GT1277] used in Western Blot (WB). GTX03189
Anti-DDB2 antibody [GT1277] used in Western Blot (WB). GTX03189
Anti-DDB2 antibody [GT1277] used in Western Blot (WB). GTX03189
Anti-DDB2 antibody [GT1277] used in Western Blot (WB). GTX03189

Cat. No. GTX03189

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 GT1277

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse
Package
100 μl ($439)
See all DDB2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
Not tested in other applications.

Calculated MW

48 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.4 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human DDB2.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

damage specific DNA binding protein 2 , DDBB , UV-DDB2 , XPE

Cellular Localization

Nucleus

Background

This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Database

Research Area

DATA IMAGES

Anti-DDB2 antibody [GT1277] used in Western Blot (WB). GTX03189

GTX03189 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with DDB2 antibody [GT1277] (GTX03189) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-DDB2 antibody [GT1277] used in Western Blot (WB). GTX03189

GTX03189 WB Image

Various whole cell extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with DDB2 antibody [GT1277] (GTX03189) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-DDB2 antibody [GT1277] used in Western Blot (WB). GTX03189

GTX03189 WB Image

WB analysis of mouse lung tissue lysate using GTX03189 DDB2 antibody [GT1277].
Dilution : 1:1000
Loading : 25μg per lane

Anti-DDB2 antibody [GT1277] used in Western Blot (WB). GTX03189

GTX03189 WB Image

WB analysis of various samples using GTX03189 DDB2 antibody [GT1277].
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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Package List Price ($)
$ 439