APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1/500 - 1/2000 |
| 1/200 - 1/1000 |
| 1/200 - 1/1000 |
| 1/10000 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
Ascites
Preservative
0.03% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Purified recombinant fragment of human DDR2 expressed in E. Coli.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
discoidin domain receptor tyrosine kinase 2 , MIG20a , NTRKR3 , TKT , TYRO10 , WRCN
Cellular Localization
Cell membrane
Background
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
![Anti-DDR2 antibody [3B11E4] used in IHC (Paraffin sections) (IHC-P). GTX83062](/templates/default/js/lightbox/images/loading.gif "Anti-DDR2 antibody [3B11E4] used in IHC (Paraffin sections) (IHC-P). GTX83062")
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GTX83062 IHC-P Image
IHC-P analysis of human skeletal muscle tissue using GTX83062 DDR2 antibody [3B11E4].
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GTX83062 WB Image
WB analysis of truncated DDR2 recombinant protein using GTX83062 DDR2 antibody [3B11E4].
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GTX83062 ICC/IF Image
ICC/IF analysis of A549 cells using GTX83062 DDR2 antibody [3B11E4].
Green : DDR2
Blue: DRAQ5 fluorescent DNA dye
Red: Actin filaments
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REFERENCE
There are currently no references for DDR2 antibody [3B11E4] (GTX83062). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for DDR2 antibody [3B11E4] (GTX83062). Be the first to share your experience with this product.
![Anti-DDR2 antibody [3B11E4] used in IHC (Paraffin sections) (IHC-P). GTX83062](/upload/website/prouct_img/small/GTX83062/GTX83062_20170912_IHC-P_w_23061322_271.webp "Anti-DDR2 antibody [3B11E4] used in IHC (Paraffin sections) (IHC-P). GTX83062")
![Anti-DDR2 antibody [3B11E4] used in Western Blot (WB). GTX83062](/upload/website/prouct_img/small/GTX83062/GTX83062_20170912_WB_w_23061322_261.webp "Anti-DDR2 antibody [3B11E4] used in Western Blot (WB). GTX83062")
![Anti-DDR2 antibody [3B11E4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83062](/upload/website/prouct_img/small/GTX83062/GTX83062_20170912_ICCIF_w_23061322_240.webp "Anti-DDR2 antibody [3B11E4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83062")
![Anti-DDR2 antibody [3B11E4] used in IHC (Paraffin sections) (IHC-P). GTX83062](/upload/website/prouct_img/normal/GTX83062/GTX83062_20170912_IHC-P_w_23061322_271.webp "Anti-DDR2 antibody [3B11E4] used in IHC (Paraffin sections) (IHC-P). GTX83062")
![Anti-DDR2 antibody [3B11E4] used in Western Blot (WB). GTX83062](/upload/website/prouct_img/normal/GTX83062/GTX83062_20170912_WB_w_23061322_261.webp "Anti-DDR2 antibody [3B11E4] used in Western Blot (WB). GTX83062")
![Anti-DDR2 antibody [3B11E4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83062](/upload/website/prouct_img/normal/GTX83062/GTX83062_20170912_ICCIF_w_23061322_240.webp "Anti-DDR2 antibody [3B11E4] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83062")