GeneTex
  • Country / Location Selection

United States (US)

DEDD2 antibody

Cat No. GTX70457

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ELISA

Reactivity

Human
Package
100 μl ($289)

APPLICATION

Application Note

Not tested. The investigator should determine the optimal dilution for a specific application such as immunohistochemistry.

Calculated MW

36 kDa. ( Note )

Specificity/Sensitivity

Reacts with residues 144-129 of the DEDD2 protein.

PROPERTIES

Form

Liquid

Buffer

100 μl serum containing 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Purification

Serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Death Effector Domain Containing 2 , Flame-3 , Flame3 , Dedd2

Background

A novel Death Effector Domain-containing protein, DEDD2, is closest in amino acid sequence homology to Death Effector Domain-containing DNA-binding protein, DEDD. DEDD2 is expressed widely in adult human tissues with highest levels in liver, kidney and peripheral blood leukocytes. DEDD2 interacts with FLIP, but not with FADD or Caspase 8. Over-expression of DEDD2 induces moderate apoptosis and results in substantial sensitization to apoptosis induced by Fas(CD95/APO-1), TRAIL(Apo2L), or FADD. These findings suggest that DEDD2 is involved in the regulation of nuclear events mediated by the extrinsic apoptosis pathway.

Database

Research Area

REFERENCE

There are currently no references for DEDD2 antibody (GTX70457). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for DEDD2 antibody (GTX70457). Be the first to share your experience with this product.
SDS
Sodium Azide.pdf
Package List Price ($)
$ 289