APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
0.2-2.5 ug/ml |
2-10 ug/ml |
Not tested in other applications.
Calculated MW
Positive Control
human fetal muscle
PROPERTIES
Form
Liquid
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human DEGS1
Purification
Affinity Purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
delta 4-desaturase, sphingolipid 1 , DEGS , DEGS-1 , DES1 , Des-1 , FADS7 , MIG15 , MLD
Cellular Localization
Mitochondrion,Endoplasmic reticulum membrane,Membrane
Background
This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010]
Database
Research Area
DATA IMAGES
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GTX46544 IHC-P Image
IHC-P analysis of human lung tissue using GTX46544 DEGS1 antibody at 1:600. Left to right:DAPI, DEGS1, Merge. Low pH, heat-induced antigen retrieval method utilizing Sodium Citrate buffer.
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GTX46544 WB Image
WB analysis of human fetal muscle tissue using GTX46544 DEGS1 antibody at 0.2-1μg/ml.
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REFERENCE
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REVIEW
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