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DFNA5 antibody, N-term

Anti-DFNA5 antibody, N-term used in Western Blot (WB). GTX81693
Anti-DFNA5 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX81693
Anti-DFNA5 antibody, N-term used in Flow cytometry (FACS). GTX81693

Cat. No. GTX81693

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, FACS

Reactivity

 Human, Mouse
Package
200 μl ($399)
See all DFNA5 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF Assay dependent
IHC-P 1:50-1:100
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 59-87 amino acids from the N-terminal region of human DFNA5.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

gasdermin E , DFNA5 , ICERE-1

Background

Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-DFNA5 antibody, N-term used in Western Blot (WB). GTX81693

GTX81693 WB Image

WB analysis of HeLa cell lysate (35ug/lane) using GTX81693 DFNA5 antibody, N-term.

Anti-DFNA5 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX81693

GTX81693 IHC-P Image

IHC-P analysis of human breast carcinoma using GTX81693 DFNA5 antibody, N-term.

Anti-DFNA5 antibody, N-term used in Flow cytometry (FACS). GTX81693

GTX81693 FACS Image

FACS analysis of MDA-MB468 cells using GTX81693 DFNA5 antibody, N-term.
Top histogram : negative control
Bottom histogram : MDA-MB468 cells

REFERENCE

Application Reference

Lv J et al. Nat Cell Biol 2022; 24 (3) : 364-372 Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1-mucin pathway.
Application : ICC/IF, IHC-P
Reactivity : Mouse
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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399