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DHTKD1 antibody

Anti-DHTKD1 antibody used in Western Blot (WB). GTX32561

Cat. No. GTX32561

Reference 4

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all DHTKD1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
Not tested in other applications.

Calculated MW

103 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human DHTKD1 (NP_061176.3).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887665

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dehydrogenase E1 and transketolase domain containing 1 , AMOXAD , CMT2Q

Cellular Localization

Mitochondrion

Background

This gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathways of several amino acids, including lysine. Mutations in this gene are associated with 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth Disease Type 2Q. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES

Anti-DHTKD1 antibody used in Western Blot (WB). GTX32561

GTX32561 WB Image

WB analysis of various sample lysates using GTX32561 DHTKD1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Leandro J et al. Hum Mol Genet 2020; 29 (7) : 1168-1179 DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo.
Zhang X et al. J Biol Chem 2020; 295 (23) : 8078-8095 Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism.
Application : WB
Jo?o Leandro et al. bioRxiv 2019; (Epub) DHTKD1 and OGDH display in vivo substrate overlap and form a hybrid ketoacid dehydrogenase complex.
Application : WB
Reactivity : Mouse
Leandro J et al. Mol Genet Metab 2019; (Epub) Mild inborn errors of metabolism in commonly used inbred mouse strains.
Application : WB
Reactivity : Mouse
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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399