GeneTex
United States (US)

DISC1 antibody [N1], N-term

GTX106286_WB_19011506_494.jpg

Cat No. GTX106286

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

94 kDa. ( Note )

Positive Control

Molt-4
PROPERTIES

Form

Liquid

Buffer

1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human DISC1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

C1orf136 antibody, FLJ13381 antibody, FLJ21640 antibody, FLJ25311 antibody, FLJ41105 antibody, KIAA0457 antibody, SCZD9 antibody, DISC1 antibody, disrupted in schizophrenia 1 protein antibody, disrupted in schizophrenia 1 antibody

Cellular Localization

Cytoplasm , Centrosome , cytoskeleton

Background

This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX106286_WB_19011506_494.jpg

GTX106286 WB Image

Sample(30 μg of whole cell lysate)
A:MOLT4(GTX27912) 7.5% SDS PAGE
GTX106286 diluted at 1:1500

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169