GeneTex
United States (US)

DISC1 antibody

Anti-DISC1 antibody used in Western Blot (WB). GTX31320
Anti-DISC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31320
Anti-DISC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31320

Cat No. GTX31320

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 - 2 μg/mL
ICC/IF 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

94 kDa. ( Note )

Positive Control

SK-N-SH Cell Lysate(GTX23956) , HeLa Cell Slide(GTX25529)

Specificity/Sensitivity

At least four isoforms of DISC1 are known to exist; this antibody will detect the three longest isoforms.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

DISC1 antibody was raised against an 18 amino acid synthetic peptide from near the center of human DISC1.The immunogen is located within amino acids 350 - 400 of DISC1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Disc1 Scaffold Protein,C1Orf136,Sczd9,Disc1

Background

This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-DISC1 antibody used in Western Blot (WB). GTX31320

GTX31320 WB Image

WB analysis of SK-N-SH cell lysate using GTX31320 DISC1 antibody.
Working concentration : (A) 0.5, (B) 1, and (C) 2 μg/ml

Anti-DISC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31320

GTX31320 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX31320 DISC1 antibody.
Working concentration : 20 μg/ml

Anti-DISC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31320

GTX31320 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX31320 DISC1 antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 329