GeneTex
United States (US)

DKC1 antibody

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GTX32562_20180530_WB_18121410_542.jpg
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GTX32562_20180530_ICCIF_18121410_769.jpg
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GTX32562_20180530_IHC-P_3_18121410_363.jpg
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GTX32562_20180530_IHC-P_8_18121410_984.jpg
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Cat No. GTX32562

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human, Mouse
See all DKC1 products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

58 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 245-514 of human DKC1 (NP_001354.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Dyskerin Pseudouridine Synthase 1,Cbf5,Dkc,Dkcx,Nap57,Nola4,Xap101,Dkc1

Background

This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Database

DATA IMAGES
GTX32562_20180530_IHC-P_12_18121410_675.jpg

GTX32562 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX32562 DKC1 antibody.
Dilution : 1:200
GTX32562_20180530_IHC-P_1_18121410_589.jpg

GTX32562 IHC-P Image

IHC-P analysis of human esophageal cancer tissue using GTX32562 DKC1 antibody.
Dilution : 1:100
GTX32562_20180530_IHC-P_2_18121410_121.jpg

GTX32562 IHC-P Image

IHC-P analysis of human esophagus tissue using GTX32562 DKC1 antibody.
Dilution : 1:100
GTX32562_20180530_WB_18121410_542.jpg

GTX32562 WB Image

WB analysis of various samples using GTX32562 DKC1 antibody.
Dilution : 1:1000
Loading : 25μg per lane
GTX32562_20180530_IHC-P_9_18121410_829.jpg

GTX32562 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX32562 DKC1 antibody.
Dilution : 1:100
GTX32562_20180530_IHC-P_5_18121410_319.jpg

GTX32562 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX32562 DKC1 antibody.
Dilution : 1:100
GTX32562_20180530_IHC-P_4_18121410_226.jpg

GTX32562 IHC-P Image

IHC-P analysis of human kidney tissue using GTX32562 DKC1 antibody.
Dilution : 1:100
GTX32562_20180530_IHC-P_18121410_907.jpg

GTX32562 IHC-P Image

IHC-P analysis of human colon tissue using GTX32562 DKC1 antibody.
Dilution : 1:100
GTX32562_20180530_IHC-P_6_18121410_330.jpg

GTX32562 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX32562 DKC1 antibody.
Dilution : 1:200
GTX32562_20180530_ICCIF_18121410_769.jpg

GTX32562 ICC/IF Image

ICC/IF analysis of U2OS cell using GTX32562 DKC1 antibody.
Blue : DAPI
GTX32562_20180530_IHC-P_13_18121410_648.jpg

GTX32562 IHC-P Image

IHC-P analysis of mouse pancreas tissue using GTX32562 DKC1 antibody.
Dilution : 1:100
GTX32562_20180530_IHC-P_3_18121410_363.jpg

GTX32562 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX32562 DKC1 antibody.
Dilution : 1:100
GTX32562_20180530_IHC-P_11_18121410_655.jpg

GTX32562 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX32562 DKC1 antibody.
Dilution : 1:100
GTX32562_20180530_IHC-P_8_18121410_984.jpg

GTX32562 IHC-P Image

IHC-P analysis of human stomach tissue using GTX32562 DKC1 antibody.
Dilution : 1:200
GTX32562_20180530_IHC-P_10_18121410_889.jpg

GTX32562 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX32562 DKC1 antibody.
Dilution : 1:200
GTX32562_20180530_IHC-P_7_18121410_308.jpg

GTX32562 IHC-P Image

IHC-P analysis of human stomach tissue using GTX32562 DKC1 antibody.
Dilution : 1:100
Package List Price ($)
$ 329