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DKC1 antibody

Anti-DKC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32562
Anti-DKC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32562
Anti-DKC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32562
Anti-DKC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32562
Anti-DKC1 antibody used in Western Blot (WB). GTX32562

Cat. No. GTX32562

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all DKC1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

58 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 245-514 of human DKC1 (NP_001354.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

dyskerin pseudouridine synthase 1 , CBF5 , DKC , DKCX , NAP57 , NOLA4 , XAP101

Background

This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Database

Research Area

DATA IMAGES

Anti-DKC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32562

GTX32562 IHC-P Image

IHC-P analysis of human cancer tissue using GTX32562 DKC1 antibody.
Dilution : 1:200

Anti-DKC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32562

GTX32562 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX32562 DKC1 antibody.
Dilution : 1:200

Anti-DKC1 antibody used in IHC (Paraffin sections) (IHC-P). GTX32562

GTX32562 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX32562 DKC1 antibody.
Dilution : 1:200

Anti-DKC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX32562

GTX32562 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX32562 DKC1 antibody.
Blue : DAPI

Anti-DKC1 antibody used in Western Blot (WB). GTX32562

GTX32562 WB Image

WB analysis of various sample lysates using GTX32562 DKC1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399